John Libbey Eurotext

European Cytokine Network

Buprenorphine differentially affects M1- and M2-polarized macrophages from human umbilical cord blood Volume 28, numéro 2, June 2017

Illustrations

  • Figure 1
  • Figure 2
  • Figure 3
  • Figure 4

Tableaux

Auteurs
Department Of Anesthesiology, Daqing Oil Field General Hospital, NO.9 Saertu District, Daqing City 163000, Heilongjiang Province, China
* Correspondence: Wei Guo. Department Of Anesthesiology, Daqing Oil Field General Hospital, NO.9 Saertu District, Daqing City 163000, Heilongjiang Province, China
a Authors contributed equally
  • Mots-clés : buprenorphine, macrophage, IRF5, downregulation, lipopolysaccharide
  • DOI : 10.1684/ecn.2017.0392
  • Page(s) : 85-92
  • Année de parution : 2017

Background

As a partial μ-opioid receptor agonist with long half-life time, buprenorphine has been widely used to relieve chronic cancer and nonmalignant pain. The maintenance of chronic pain involves inflammation; however whether buprenorphine has anti-inflammation property remains unclear.