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Buprenorphine differentially affects M1- and M2-polarized macrophages from human umbilical cord blood Volume 28, numéro 2, June 2017

Illustrations


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Tableaux

Auteurs
Department Of Anesthesiology, Daqing Oil Field General Hospital, NO.9 Saertu District, Daqing City 163000, Heilongjiang Province, China
* Correspondence: Wei Guo. Department Of Anesthesiology, Daqing Oil Field General Hospital, NO.9 Saertu District, Daqing City 163000, Heilongjiang Province, China
a Authors contributed equally

Background

As a partial μ-opioid receptor agonist with long half-life time, buprenorphine has been widely used to relieve chronic cancer and nonmalignant pain. The maintenance of chronic pain involves inflammation; however whether buprenorphine has anti-inflammation property remains unclear.