John Libbey Eurotext

European Journal of Dermatology

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Contact pemphigus: does it exist?Contact pemphigus Article à paraître

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Auteurs
1 Department of Dermatology and Venereology, Acibadem City clinic Tokuda Hospital - Sofia
2 Department of Dermatology and Venereology, Medical Faculty, Trakia University- Stara Zagora, Bulgaria
3 Department of Dermatology and Venereology, Medical Faculty, Medical University- Sofia, Bulgaria
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The entity “contact pemphigus” has been recognized for more than 50 years, however existence of the disease, which is opposed and supported by many, is questionable. Contact pemphigus is defined as pemphigus occurring at the site of local skin contact with different chemicals. Many products have been disclosed as aetiological factors such as pesticides, topical drugs (imiquimod, ketoprofen, phenol, bezoin, polymyxin B sulphate, neomycin and bacitracin), cosmetics, garlic and others. This paper summarizes the current knowledge on contact pemphigus and the chemicals responsible for its aetiology, with an emphasis on mechanisms that may elicit the disease.