Médecine et Santé Tropicales
MENULe traitement antirétroviral à base de trois inhibiteurs nucléosidiques de la transcriptase inverse chez les patients naïfs infectés par le VIH à Abidjan (Côte d’Ivoire) Volume 22, numéro 3, Juillet-Août-Septembre 2012
Auteurs
Service des maladies infectieuses et tropicales, CHU de Treichville, Abidjan, Côte d’Ivoire
- Mots-clés : antiretroviral treatment, nucleoside analog reverse transcriptase inhibitors, HIV, Côte d’Ivoire
- DOI : 10.1684/mst.2012.0092
- Page(s) : 333-4
- Année de parution : 2012
<p>This study assesses the results of initial antiretroviral therapy with 3 nucleoside reverse transcriptase inhibitors over the first 12 months of treatment.</p><p>Patients’ general health improved significantly during the year, with a significant mean weight gain (from 59.3 kg to 65.12 kg) and a strong regression in the frequency of opportunistic infections over the study period, from 38% to 2% (P<0.0001). The mean CD4 T-cell count rose from 242.8 to 390.5 cell/mm 3, for a mean increase of 147.7 cells/mm 3.</p><p>Accordingly, antiretroviral treatment with three nucleoside reverse transcriptase inhibitors is effective and is a useful alternative in a country with limited resources.</p>