John Libbey Eurotext

Magnesium Research

Magnesium chloride or magnesium sulfate: a genuine question Volume 18, issue 3, September 2005

  • Auteur(s) : Jean Durlach, Andrée Guiet-Bara, Nicole Pagès, Pierre Bac, Michel Bara , SDRM, 64 rue de Lonchamp, 92200 Neuilly, France, Laboratoire de physiologie et physiopathologie, Université P. et M. Curie, Paris, France, Laboratoire de toxicologie, Faculté de pharmacie, Université Louis Pasteur, Strasbourg, 67400 Illkirch-Grafenstaden, France, Laboratoire de pharmacologie, Faculté de pharmacie, Paris XI, Pierre Maurois, 92290 Chatenay-Malabry, France
  • Mots-clés : chloride, magnesium, sulfate
  • Page(s) : 187-92
  • Année de parution : 2005

MgSO 4 is routinely used in therapeutics despite its toxicity. The aim of the present review was to compare MgSO 4 and MgCl 2 effects in order to answer the question whether MgSO 4 could be or not replaced by MgCl 2. Considering that the two salts have both similar and proper effects, a clear-cut conclusion is not easy to draw. However, choosing MgCl 2 seems advisable because of its more interesting clinical and pharmacological effects and its lower tissue toxicity as compared to MgSO 4.