John Libbey Eurotext

European Journal of Dermatology

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Ustekinumab in patients previously treated with TNFα inhibitors: a real-life study Volume 28, numéro 1, January-February 2018

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Auteurs
Dermatology Department, Hospital Santo António dos Capuchos, Centro Hospitalar de Lisboa Central, Alameda Santo António dos Capuchos 1169-050, Lisbon, Portugal

Biological treatment strategies for severe psoriasis have been evolving. New agents and combination therapies are valid strategies for the management of refractory patients. Nevertheless, the response to a subsequent biological agent is still a matter of debate. For anti-TNFα agents, it is established that the response to a second agent is compromised after failure of the first [1, 2]. Some studies suggest that lack of efficacy of an anti-TNFα is a risk factor for subsequent ustekinumab failure [...]