John Libbey Eurotext

European Journal of Dermatology


Transverse leukonychia in severe hypocalcemia Volume 14, numéro 1, January-February 2004

Unit of Dermatology, Department of Internal Medicine, Immunology and Infectious Diseases, University of Bari, Piazza Giulio Cesare 11, 70124 Bari, Italy Istituto Dermopatico dell‘Immacolata, I.D.I., I.R.C.C.S., 00167, Rome, Italy Section of Internal Medicine, Department of Internal Medicine and Public Medicine, University of Bari, Piazza Giulio Cesare 11, 70124 Bari, Italy
  • Mots-clés : celiac disease, hypocalcemia, hypoparathyroidism, nails, transverse leukonychia
  • Page(s) : 67-8
  • Année de parution : 2004

We report the case of a 26‐year‐old man with acral tetany and muscular cramps of the upper limbs associated with hypocalcemia caused by hypoparathyroidism and celiac disease. Physical examination revealed a transverse leukonychia which disappeared after treatment with calcium lactogluconate, calcium carbonate and calcitriol. Hypocalcemia may induce nail alterations with a double mechanism represented by angiospasm and disorganization of the hard keratin and of the integrin subunits.