Department of Dermatology and Venereology, Innsbruck, Austria.
- Page(s) : 353-7
- Année de parution : 2000
Dermatomycoses can be treated effectively with oral griseofulvin or ketoconazole
but the necessity for relatively long-term therapy and the significant
incidence of gastrointestinal complaints and headache have restricted
the use of these agents to recalcitrant infections [1-9].
Itraconazole (Sporanox®, Janssen, Beerse, Belgium) is
a triazole derivative that potently inhibits the cytochrome P450-dependent
enzyme, 14alpha-demethylase [...]