John Libbey Eurotext

European Journal of Dermatology


Sclerodermiform porphyria cutanea tarda after torasemide Volume 25, numéro 5, September-October 2015


  • Figure 1
Medical University Graz,
Department of Dermatology,
Auenbruggerplatz 8, 8036 Graz, Austria

Porphyria cutanea tarda (PCT), a late onset hepatic porphyria, develops when the activity of uroporphyrinogen decarboxylase (Uro-D) is decreased. The acquired type, induced by liver disease or drugs, is common. Typical cutaneous symptoms include skin fragility, vesicles, bullous lesions, atrophic scars, facial hypertrichosis, hyperpigmentation and scarring alopecia [1]. Pseudoscleroderma occurs in 15-18% of patients with an underlying liver disease or in patients on maintenance hemodialysis [2, 3]. [...]