John Libbey Eurotext

European Journal of Dermatology


Reactivity to anti-RNA polymerase III antibody and nailfold capillary changes in patient with generalized morphea combined with multiple autoimmune disorders Volume 28, numéro 1, January-February 2018


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Department of Dermatology, Nara Medical University School of Medicine, 840 Shijo, Kashihara, Nara 634-8522, Japan

Morphea, also called localized scleroderma, can be differentiated from systemic scleroderma (SSc) by the absence of Raynaud phenomenon, sclerodactyly, and nailfold capillary changes [1]. Anti-RNA polymerase III (anti-RNAP III) antibody (Ab) is one of the most common antinuclear autoantibodies found in SSc, along with anti-centromere and anti-Scl-70 Ab [2]. We report a patient with generalized morphea (GM) who exhibited nailfold changes and reactivity to anti-RNAP III Ab.A 78-year-old female had noticed [...]