John Libbey Eurotext

European Journal of Dermatology


Psoriasis beyond the skin: a review of the literature on cardiometabolic and psychological co-morbidities of psoriasis Volume 24, numéro 3, May-June 2014


1 Department of Dermatology,
Hospital de la Santa Creu i Sant Pau,
Universitat Autònoma de Barcelona,
Sant Antoni Maria Claret 167,
08025 Barcelona, Spain
2 St Vincent's University Hospital,
Elm Park,
Dublin, Ireland
3 Lotus Mallbris,
Pfizer Global Medical Dermatology Lead,
Philadelphia, USA
4 Department of Dermatology,
Federal Academic Teaching Hospital,
Feldkirch, Austria
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  • Mots-clés : cardiovascular, co-morbidities, psoriasis, psychological
  • DOI : 10.1684/ejd.2014.2299
  • Page(s) : 305-11
  • Année de parution : 2014

Psoriasis is increasingly associated with a range of co-morbid diseases and risk factors. Patients with co-morbidities are more likely to need hospitalisation for non-dermatological conditions, and incur greater total costs than those without co-morbidities. A literature review was conducted on two of the most common co-morbidities of psoriasis (cardiovascular (CV) and psychological co-morbidities), to establish their incidence and impact and to raise awareness of unanswered questions and highlight knowledge gaps. A large number of small controlled or cross-sectional studies report increased prevalence of cardiometabolic and psychological co-morbidities in psoriasis patients. A number of large cohort studies documented the incidence of various cardiometabolic co-morbidities. Severe psoriasis is associated with increased mortality, and the most common cause of death is CV disease. Studies on the management of co-morbidities and their impact on psoriasis treatment are scarce. Many questions on the co-morbidities of psoriasis remain to be answered.