John Libbey Eurotext

European Journal of Dermatology


Progressive nodular histiocytosis improved by methotrexate Volume 27, numéro 6, November-December 2017


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1 Department of Dermatology and Venerology,
2 Department of Pathology, University Hospital of Brest, 29609 Brest, France

Non-Langerhans cell histiocytoses (NLHs) represent a heterogeneous group of uncommon disorders [1]. Their classification, based on clinical, histological, immuno-histochemical, and evolving features, is difficult [2]. Moreover, both mixed and transitional forms between the different entities have been described. The rarity of cases and existence of different spontaneously-regressive entities account for the lack of standardized treatments. The treatment is often disappointing and therapeutic successes, [...]