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European Journal of Dermatology

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Photosensitive drug eruption induced by flutamide Volume 8, numéro 6, September 1998

Auteurs
Department of Dermatology, National Takasaki Hospital, 36, Takamatsucho, Takasaki 370-0829, Japan.
  • Page(s) : 427-9
  • Année de parution : 1998

Flutamide (FLU; 2-metyl-N-[4-nitro-3-8-trifluorometyl-9 phenyl] propamide; molecular weight, 276.22; half-life, 1.4 hours) (Fig. 1) is a non-steroidal anti-androgen commonly used for the treatment of prostatic carcinoma [1-3]. This drug was first brought onto the market in 1987, and has been used in Japan since 1994. To our knowledge, there are only two reports in the English literature describing photoallergic reaction induced [...]