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European Journal of Dermatology

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Macrolide immunosuppressants Volume 9, numéro 5, July - August 1999

Auteur
Department of Dermatology, University of Kiel, Schittenhelmstr. 7, 24105 Kiel, Germany.
  • Page(s) : 346-51
  • Année de parution : 1999

Macrolides have been known for decades to physicians as antibiotics of preference for use with children and for a number of special indications such as legionellosis and mycoplasma infections. During a screening program for naturally occuring immunosuppressants, in 1984, Fujisawa Pharmaceutical Company isolated a 822 kDa macrolide compound with potent T cell inhibitory activity from the fermentation broth of Streptomyces tsukubaensis, [...]