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European Journal of Dermatology

Leg ulcers: A new symptom of Blau syndrome? Volume 18, issue 6, Novembre-Décembre 2008

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  • Auteur(s) : Veerle Dhondt, Sarah Hofman, Karin Dahan, Hilde Beele , Department of Dermatology, University Hospital of Ghent, De Pintelaan 185, 9000 Ghent, Belgium, Centre de génétique humaine, Université Catholique de Louvain, Av. E. Mounier, 1200 Bruxelles, Belgium
  • Mots-clés : Blau syndrome, granulomatous dermatosis, leg ulcers
  • Page(s) : 635-7
  • DOI : 10.1684/ejd.2008.0510
  • Année de parution : 2008

Blau syndrome is a rare autosomal dominant condition, typically defined by granulomatous polyarthritis, uveitis and skin eruption. Biopsy specimens demonstrate non-caseating granulomas in all lesions. We present a case of Blau syndrome associated with large recalcitrant leg ulcers. Biopsies taken in the leg ulcers of our patient systematically showed granulomas. Although leg ulcers have not previously been described as a part of Blau syndrome, we assume that the ulcerations in this case form part of Blau syndrome.