JLE

European Journal of Dermatology

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Langerhans cells are susceptible to measles virus infection and actively suppress T cell proliferation Volume 8, numéro 6, September 1998

Auteurs
INSERM U. 404 “Immunité et Vaccination”, Bât. Pasteur, av. Tony-Garnier, 69365 Lyon Cedex 07, France.
  • Page(s) : 413-20
  • Année de parution : 1998

LC represent an immature type of DC located in various epithelial tissues including the skin and mucosae, and are considered as sentinels responsible for the uptake and processing of foreign antigens and activation of naive T cells upon migration to draining lymphoid organs. As such, they represent the first antigen-presenting cell type exposed to pathogens which penetrate via mucosal routes. Although LC are not very efficient at stimulating [...]