John Libbey Eurotext

European Journal of Dermatology


Impetigo herpetiformis with IL-36RN mutation successfully treated with secukinumab Volume 28, numéro 3, May-June 2018


  • Figure 1
1 Department of Dermatology, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan
2 Department of Dermatology, Nagoya University Graduate School of Medicine, Nagoya, Japan
3 Department of Dermatology, Yamanashi Prefectural Central Hospital, Yamanashi, Japan
4 Department of Dermatology, Fujita Health University School of Medicine, Aichi, Japan

A Japanese female with a history of psoriasis vulgaris, but not of generalized pustular psoriasis (GPP) and impetigo herpetiformis (IH), had a second pregnancy without any disease eruption until the 37th week of pregnancy. At the 38th week, oedematous red plaques with pustules rapidly appeared on her limbs and trunk, in particular, congregating in the abdominal area (figure 1A-C). These eruptions were accompanied by fever, but no other systemic symptoms. A skin biopsy specimen showed mild psoriasiform [...]