John Libbey Eurotext

European Journal of Dermatology


Immunohistochemical localization of activated and mature CD83+ dendritic cells in granulomas of sporotrichosis Volume 11, numéro 6, November - December 2001

Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-ku, J-812-8582 Fukuoka, Japan.
  • Page(s) : 527-9
  • Année de parution : 2001

Dendritic cells (DC) are the most potent antigen-presenting cells (APC) and are believed to be crucial for the initiation of T cell response to foreign antigens [1]. DC in the skin capture and process antigens, undergo activation, migrate to lymphoid organs and secrete cytokines to initiate the immune response. Fully mature and activated DC are characterized by the expression of CD83, a member of the immunoglobulin superfamily [2]. Langerhans cells [...]