Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, 3-1-1, Maidashi, Higashi-ku, J-812-8582 Fukuoka, Japan.
- Page(s) : 527-9
- Année de parution : 2001
Dendritic cells (DC) are the most potent antigen-presenting cells (APC)
and are believed to be crucial for the initiation of T cell response to
foreign antigens . DC in the skin capture and process antigens, undergo
activation, migrate to lymphoid organs and secrete cytokines to initiate
the immune response. Fully mature and activated DC are characterized by
the expression of CD83, a member of the immunoglobulin superfamily .
Langerhans cells [...]