John Libbey Eurotext

European Journal of Dermatology


IgA-mediated leukaemic vasculitis in a patient with rapid progression of myelodysplastic syndrome to acute myeloid leukaemia Volume 27, numéro 3, May-June 2017


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1 Department of Dermatology
2 Department of Pathology,
Graduate School of Medical and Dental Sciences,
Tokyo Medical and Dental University,
1-5-45, Yushima, Bunkyo-ku, Tokyo,
113-8510 Japan

Leukaemic vasculitis is extremely rare in patients with myelodysplastic syndrome (MDS). Although an immunoglobulin (Ig) A-mediated mechanism has been speculated to participate in its pathogenesis, detection of IgA deposition by direct immunofluorescence (IF) has not been so far reported [1]. We describe, herein, a case of leukaemic vasculitis in a patient with MDS and clearly show IgA deposits on vessel walls.A 79-year-old man presented with multiple erythematous plaques on his trunk and limbs. He [...]