JLE

European Journal of Dermatology

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HLA-DRB1 and HLA-DQB1 genes in susceptibility and resistance to cicatricial pemphigoid in French Caucasians Volume 8, numéro 5, July - August 1998

Auteurs
Department of Dermatology, University Hospital Debré, Reims, France.
  • Page(s) : 330-3
  • Année de parution : 1998

Cicatricial pemphigoid (CP) is an autoimmune, subepithelial bullous disease, affecting primarily the elderly. CP patients typically present with tense, subepithelial blisters and erosions of mucosae (oral, ocular, and or genital epithelia) with varying degrees of skin involvement and further scar formation [1, 2]. As in other autoimmune skin-blistering diseases, there is in vivo deposition of immunoglobulins (Ig) and complement components [...]