John Libbey Eurotext

European Journal of Dermatology


Foreign body reaction three years after injection with polycaprolactone (Ellanse®) Volume 27, numéro 5, September-October 2017


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1 Department of Dermatology,
2 Department of Pathology, Kyungpook National University School of Medicine,

Filler injections are commonly performed for facial rejuvenation and volume replacement. Injectable polycaprolactone (PCL) derivatives are widely used as soft tissue fillers for aesthetic facial enhancement. PCL is a synthetic linear polyester with almost 50% crystallinity, and consists of 6-hydroxyhexanoates. PCL is a soft dermal filler based on PCL microspheres (range: 25-50 μm); it is non-toxic and biodegradable, and is completely excreted from the human body in two stages. The first stage starts [...]