John Libbey Eurotext

European Journal of Dermatology


Finasteride improves male pattern hair loss in a randomized study in identical twins Volume 12, numéro 1, January - February 2002

Merck Research Laboratories, 126 East Lincoln Avenue, RY33-500, Rahway, NJ 07065, USA.
  • Page(s) : 32-7
  • Année de parution : 2002

Male pattern hair loss (MPHL) affects 50% of men by the age of 50 [1, 2]. This condition is thought to be under genetic control, occurring in males with an inherited sensitivity of scalp hair follicles to the deleterious effects of androgens [3, 4]. Subjects with a defect in the enzyme 5*-reductase (5*R) type 2, which converts testosterone into dihydrotestosterone (DHT), do not develop MPHL, suggesting that this condition can be prevented [...]