John Libbey Eurotext

European Journal of Dermatology


Dermoscopy and confocal microscopy for metachronous multiple melanomas: morphological, clinical, and molecular correlations Volume 28, numéro 2, March-April 2018

Ignazio Stanganelli for the Italian Melanoma Intergroup (IMI)b 2 6
1 Unit of Cancer Genetics, Institute of Biomolecular Chemistry (ICB), National Research Council (CNR), Traversa La Crucca 3, 07100, Sassari, Italy
2 Experimental Pathology and Oncology, Department of Clinical and Experimental Medicine, University of Sassari, Via Padre Manzella 4, 07100, Sassari, Italy
3 Dermatologic Unit, University of Parma, 43121 Parma, Italy
4 Anatomic Pathology Unit, Department of Surgical, Microsurgical and Medical Sciences, University of Sassari, Via Matteotti 64, 07100, Sassari, Italy
5 Dermatology Unit, Department of Clinical and Experimental Medicine, University of Sassari, V.le San Pietro 43, 07100, Sassari, Italy
6 Skin Cancer Unit, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST), Meldola, FC, Italy
* Reprints
a These authors contributed equally
b IMI includes the following additional members who participated as investigators in this study and should be considered as co-authors: Gerardo Botti and Corrado Caracò (Istituto Nazionale Tumori Fondazione Pascale, Napoli, Italy), Vanna Chiarion Sileni (Istituto Oncologico Veneto, Padova, Italy), Anna Maria Di Giacomo (Azienda Ospedaliera Universitaria Senese, Siena, Italy), Mario Mandalà (Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy), Pietro Quaglino (Azienda Ospedaliera Universitaria Città Salute e Scienza, Torino, Italy), and Paola Queirolo (Azienda Ospedaliera Universitaria San Martino, Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy)
  • Mots-clés : cancer, melanoma, dermoscopy, confocal microscopy, BRAF, NRAS
  • DOI : 10.1684/ejd.2017.3206
  • Page(s) : 149-56
  • Année de parution : 2018


Cutaneous melanoma is one of the most frequent malignancies of the skin in Caucasian populations. Patients who develop cutaneous melanoma are at increased risk of developing a second primary melanoma. The estimated incidence of multiple primary melanoma (MPM) ranges from 1.2% to 8.2% of cases, with a high preponderance of melanomas occurring metachronously.