John Libbey Eurotext

European Journal of Dermatology

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Cowden disease or multiple hamartoma syndrome - cutaneous clue to internal malignancy Volume 12, numéro 5, September - October 2002

Auteurs
Department of Dermatology, University Hospital Basel, Petersgraben 4, 4031 Basel, Switzerland.
  • Page(s) : 411-21
  • Année de parution : 2002

Skin tumors may serve as markers for inheritable disorders and may herald internal malignancy [1]. Cowden disease (CD, MIM #158350) as well as Muir-Torre syndrome, Gardner syndrome, multiple endocrine neoplasia 1 and 2B, tuberous sclerosis and neurofibromatosis 1 and 2 are familial cancer predisposition syndromes, all of which exhibit mostly benign cutaneous tumors indicative of internal malignancies. An extensive review of this field has recently [...]