John Libbey Eurotext

European Journal of Dermatology

Confirmation of the association between male pattern baldness and the androgen receptor gene Volume 15, numéro 5, September-October 2005

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  • Auteur(s) : Etgar Levy-Nissenbaum, Michal Bar-Natan, Moshe Frydman, Elon Pras , Danek Gartner Institute of Human Genetics, Sheba Medical Center, Tel Hashomer, Israel; affiliated to The Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
  • Mots-clés : male pattern baldness, androgen receptor, single nucleotide polymorphism
  • Page(s) : 339-40
  • Année de parution : 2005

Male pattern baldness (MPB) is a common phenomenon with a complex mode of inheritance. A recent report has implicated the androgen receptor gene in MPB, but this result has not been confirmed. We analyzed a silent polymorphism in the androgen receptor gene (AR) in a group of 41 bald males and 39 non-bald males, and found a significant association (p < 0.0026), thus confirming the previously reported association between MPB and the AR gene.