John Libbey Eurotext

European Journal of Dermatology


Basophil and M2 macrophage infiltration in lesional skin of eosinophilic granulomatosis with polyangiitis Volume 27, numéro 5, September-October 2017


  • Figure 1
Department of Dermatology, Kyoto University Graduate School of Medicine, Japan

Eosinophilic granulomatosis with polyangiitis (EGPA; known formerly as Churg-Strauss syndrome) is a disease involving multiple organs, and is characterized by systemic vasculitis, blood and tissue eosinophilia, and bronchial asthma [1]. Cutaneous manifestations are observed in 40% of EGPA patients [2], including leukocytoclastic/necrotizing vasculitis and eosinophilic tissue infiltration. Although the aetiology of EGPA remains largely unknown, it has been postulated that a T-helper 2 (Th2) cytokine-dominant [...]