European Journal of Dermatology


B-cell lymphomatoid contact dermatitis caused by methylisothiazolinone and methylchloroisothiazolinone Volume 28, numéro 1, January-February 2018


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1 Department of Dermatology, University Hospitals KU Leuven, Kapucijnenvoer 33, B-3000 Leuven, Belgium
2 Department of Dermatopathology, University Hospitals Leuven - KU Leuven, Herestraat 49, B-3000 Leuven, Belgium

The clinical and histological expression of allergic contact dermatitis may resemble a cutaneous B- or T-cell lymphoma, such as “lymphomatoid contact dermatitis”. This entity was first described in 1976 by Orbaneja et al. [1], and is chronic and persistent allergic contact dermatitis, which is included in the class of cutaneous lymphoid hyperplasias, a mixed group of benign T- or B-cell lympho-proliferative disorders with clinical and histological features resembling true lymphoma [2]. As stated [...]