John Libbey Eurotext

European Journal of Dermatology


Acute generalized exanthematous pustulosis induced by terbinafine Volume 13, numéro 3, May 2003

Department of Dermatology, Hospital de Son Llàtzer, Carretera de Manacor, Km. 4, Son Ferriol, 07198 Palma de Mallorca, Spain. Department of Dermatology, Hospital de la Santa Creu i de Sant Pau, Barcelona, Spain

Terbinafine is an allylamine fungicidal agent that is widely used for the treatment of onychomycoses and other fungal infections. Adverse effects may occur in more than 10% of patients receiving oral terbinafine, with cutaneous reactions in 2.7%. We describe the development of acute generalized exanthematous pustulosis in a 36-year-old woman who took oral terbinafine.