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European Cytokine Network

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Stem cell factor-deficient mice have a dysregulation of cytokine production during local inflammation Volume 9, numéro 1, March 1998

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INTRODUCTION A role for mast cells has been demonstrated in various disease conditions, such as IgE-dependent immediate hypersensitivity, inflammatory bowel disease, rheumatoid arthritis and asthma [1-3]. One way in which mast cells contribute to the pathogenesis of inflammatory diseases is by producing cytokines. In fact, mast cells produce both pro- and anti-inflammatory cytokines. For example, IL-1, IL-3, IL-4, IL-5, [...]