John Libbey Eurotext

European Cytokine Network


Sophocarpine suppress inflammatory response in human fibroblast-like synoviocytes and in mice with collagen-induced arthritis Volume 28, numéro 3, September 2017


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1 Department of Rheumatism, Daqing Oil Field General Hospital, NO.9 Saertu District, Daqing City 163000, Heilongjiang Province, China</i>
2 Department of Rehabilitation, Daqing Donghai Hospital, NO.13 Chengbei Road, Ranghulu District, Daqing City 163000, Heilongjiang Province, China
* Correspondence: L. Zhu
a Authorscontributed equally to this work
  • Mots-clés : rheumatoid arthritis, fibroblast-like synoviocytes, sophocarpine, proinflammatory cytokines, mitogen-activated protein kinase (MAPK)
  • DOI : 10.1684/ecn.2017.0400
  • Page(s) : 120-6
  • Année de parution : 2017


Rheumatoid arthritis (RA) is a chronic autoimmune disease affecting nearly 1% of adults worldwide. This study aimed to investigate whether sophocarpine is a potential drug for treating RA.