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European Cytokine Network

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Interleukin-1beta and interferon-gamma differentially regulate release of monocyte chemotactic protein-1 and interleukin-8 by human bronchial epithelial cells. Volume 9, numéro 3, September 1998

Auteurs
Department of Immunology, Erasmus University and University Hospital Dijkzigt, Rotterdam, The Netherlands

INTRODUCTION Asthma is a chronic inflammatory disease of the airways. The inflammatory process is characterized by an accumulation of activated leukocytes, predominantly macrophages, T lymphocytes and eosinophils, in the bronchial wall [1]. The recruitment of peripheral blood leukocytes into the airways is mediated through several signals, including adhesion molecules and chemotactic factors produced at the inflammatory focus. [...]