European Cytokine Network
MENUFunctional epitope mapping of human interleukin-1 b y surface plasmon resonance Volume 8, numéro 2, June 1997
Illustrations
- Mots-clés : antibodies, cytokines, cytokine receptors, surface plasmon resonance
- Page(s) : 161-71
- Année de parution : 1997
INTRODUCTION IL-1 is a family of related proteins representing a prototypic, multifunctional cytokine. Among its multiple functions in virtually every cell type, IL-1 is one of the major mediators of host defense reactions against invasion, acting as a stimulator of the immune response mechanisms and as an initiator of inflammation-related defensive events [1, 2]. The high inflammatory activity of IL-1 leads to the need for [...]