European Cytokine Network
MENUEvaluation of tumor necrosis factor alpha production in ex vivo short term culture whole blood from women with polycystic ovary syndrome Volume 13, numéro 4, December 2002
Illustrations
A Veronica Araya, Adam Aguirre, Carmen Romero, Cristian Miranda, Maria Carmen Molina, Arturo Ferreira
Seccion Endocrinologia, Hospital Clinico de la U. de Chile, Santos Dumont 999, Independencia, Santiago, Chile.
- Page(s) : 419-24
- Année de parution : 2003
Introduction Tumor necrosis factor alpha (TNFa) is one of the most pleiotropic cytokines in mammals and, among its wide array of biological functions, effects on regulation of ovarian function have been described [1, 2]. Thus, chronic anovulation, oligo or amenorrhea, infertility, hyperandrogenism, obesity, insulin resistance and higher TNF-a serum levels have been detected in women affected by polycystic ovary syndrome (PCOS), one of the [...]