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European Cytokine Network

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Effects of interleukin-2 therapy on the proliferation and differentiation of CD4/CD25 positive and CD4/CD25 negative cells in HIV+ patients Volume 12, numéro 3, September 2001

Auteurs
Microbiology, Immunology and Virology, Centro di Riferimento Oncologico, Aviano, Italy.
  • Page(s) : 430-6
  • Année de parution : 2001

INTRODUCTION Antiretroviral therapy has been shown to reduce HIV-1 replication, to raise CD4 counts and to produce a progressive, although incomplete, increase in CD4 T cell functions [1-7]. Based on the available data, it is now widely accepted that alternative approaches, supplementing HAART, are necessary to increase immune functions and to reduce viral replication to a maximum extent in HIV-infected individuals [8, 9]. Interleukin-2 [...]