John Libbey Eurotext

European Cytokine Network

BCG-induced interleukin-6 upregulation and BCG internalization in well and poorly differentiated human bladder cancer cell lines Volume 9, numéro 2, June 1998


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INTRODUCTION Intravesical BCG therapy has been successfully used for the treatment of superficial bladder cancer [1, 2]. For BCG therapy to be effective, the development of an immune response seems to be important, although the exact mechanism remains to be established [3]. For the initiation of the immune reaction, several steps during the first interaction of BCG with the bladder wall have been suggested to be involved....