Motor function over seven days following traumatic brain injury in rats as assessed using the rotarod motor test. Animals treated at 30 min after injury with 25 μmol/kg MgCl2 in polyethylene glycol performed significantly better (p<0.05) than animals treated with the optimal dose of 254 μmol/kg MgCl2 alone. Both groups treated with MgCl2 (either with or without polyethylene glycol) performed significantly better (p<0.001) than vehicle-treated controls For clarity, significance symbols have been omitted. □ Sham (noninjured) animals; ● 25 μmol/kg MgCl2 in polyethylene glycol; ■ 254 μmol/kg MgCl2 alone; ○ vehicle treated animals. Adapted from Busingye et al., .