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European Cytokine Network

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Tumor necrosis factor-alpha and interleukin-6 are differently expressed by fresh human cancerous ovarian tissue and primary cell lines Volume 9, numéro 2, June 1998

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INTRODUCTION The human ovary is not considered an immunologically privileged site. Resident ovarian mononuclear phagocytes, lymphocytes, and polymorphonuclear granulocytes can be observed at various stages of the ovarian life cycle [1, 2]. Interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) are autocrine/paracrine polypeptide cytokines with pleiotropic activities that play a central role in host defense including [...]