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Compromised IFN-gamma production in the elderly leads to both acute and latent viral antigen stimulation: contribution to the immune risk phenotype? Volume 13, numéro 4, December 2002

Auteurs
Center for Medical Research, ZMF, Waldhšrnlestr. 22, D-72072 Tuebingen, Germany.
  • Page(s) : 387-3
  • Année de parution : 2003

Introduction The elderly have an increased incidence of many infectious diseases, accompanied by increases in morbidity and mortality. This is considered to be associated with impaired immune responses due to age-associated decreased immune function [1]. Pulmonary infections, such as viral and bacterial pneumonia and influenza, all occur at higher rates in elderly people. It has been proposed that immunodeficiency in the elderly is primarily [...]