Magnesium Research


The COVID-19 pandemic: is there a role for magnesium? Hypotheses and perspectives Volume 33, numéro 2, April-May-June 2020


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1 University of Bologna, Department of Pharmacy and Biotechnology, BolognaItaly
2 Università Cattolica del Sacro Cuore-Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Dipartimento di Medicina e Chirurgia Traslazionale, RomaItaly
3 Université Clermont Auvergne, INRAE, unité de nutrition humaine (UNH), Clermont-FerrandFrance
4 Università di Milano, Department of Biomedical and Clinical Sciences L. Sacco, MilanItaly
* Correspondence

More and more studies are accumulating about COVID-19. Some aspects of the pathogenesis of the disease recall events occurring in Mg deficiency, such as a drop of T cells, increased plasma concentration of inflammatory cytokines, and endothelial dysfunction. We hypothesize that a low Mg status, which is rather common, might foment the transition from mild to critical clinical manifestations of the disease. Epidemiological, clinical, and fundamental research is needed to clarify the potential role of Mg deficiency in COVID-19.