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Correct estimates of hydrated ionic radius should be used when discussing the permeation of topically applied magnesium ions Volume 32, numéro 1, January-February-March 2019

Auteurs
1 Evolve Group, 15 Titanium Ct, Crestmead, Queensland 4132, Australia
2 Charles Darwin University, Ellengowan Dr, Casuarina, Darwin, Northern Territory 0810, Australia
3 The University of Queensland, School of Chemistry and Molecular Biosciences and ARC Training Centre for Biopharmaceutical Innovation, Brisbane, Queensland 4072, Australia

Dear Editor, Our work published in Magnesium Research in 2016 [1] used a Franz cell model to demonstrate that magnesium ions could permeate the human stratum corneum, and that this process was facilitated by hair follicles. Many physical and biological factors influence the ability of ions to permeate tissues and membranes. These include interactions with tissue matrix, presence of specific ion transporters, and the size of the hydrated ion. The size of a hydrated ion would be expected to impose [...]