JLE

Hématologie

MENU

Dynamique moléculaire de la transformation des progéniteurs myéloïdes Volume 29, numéro 1, Janvier-Février 2023

Illustrations

Auteurs
1 Équipe 2, C3M, Inserm U1065, Nice, France
2 Institut de génétique et développement de Rennes (IGDR), Université Rennes 1, CNRS, UMR6290, Inserm ERL U1305, Rennes, France
* Tirés à part : ML Arcangeli
Links of interest: Authors have no link of interest regarding this article.

  Acute myeloid leukaemia (AML) is the most common acute leukaemia in adults. AML results from the accumulation of abnormal immature myeloid progenitors, also called blasts, that are blocked in their differentiation. AML is a very heterogeneous disease with more than a dozen of genetically distinct entities (See new AML classification from [1]). Each genetically distinct AML subgroup is generally defined by gene mutations and/or alterations related to its aggressiveness, and is associated to [...]