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Indications and procedure for CAR T-cell infusion Article à paraître

Figure 1

Selection procedure for patients with relapsed or refractory diffuse large B-cell lymphoma. R/R = relapsed or refractory. CNS = Central Nervous System.

Figure 2

Form for selecting patients for a CAR-T programme (Department of Haemato-Oncology, Hospital Saint Louis, Paris).

Figure 3

Rules for stopping immunosuppressive drugs/chemotherapies/targeted therapies before cytapheresis. DLI = donor lymphocyte injection. GVH = graft versus host disease [12, 16].

Figure 4

Rules for stopping immunosuppressive drugs/chemotherapies/targeted therapies before reinjection of CAR-T cells. TKIs = tyrosine kinase inhibitors [12, 16].

Figure 5

Treatment algorithm for the management of CRS, according to its severity grade, following Yakoub-Agha et al[12].

Figure 6

Treatment algorithm for the management of ICANS, according to its severity grade, following Yakoub-Agha et al.[12].

Figure 7

Patient care pathway from screening to long-term follow-up and kinetics of complications.