Selection procedure for patients with relapsed or refractory diffuse large B-cell lymphoma. R/R = relapsed or refractory. CNS = Central Nervous System.
Form for selecting patients for a CAR-T programme (Department of Haemato-Oncology, Hospital Saint Louis, Paris).
Rules for stopping immunosuppressive drugs/chemotherapies/targeted therapies before cytapheresis. DLI = donor lymphocyte injection. GVH = graft versus host disease [12, 16].
Rules for stopping immunosuppressive drugs/chemotherapies/targeted therapies before reinjection of CAR-T cells. TKIs = tyrosine kinase inhibitors [12, 16].
Treatment algorithm for the management of CRS, according to its severity grade, following Yakoub-Agha et al[12].
Treatment algorithm for the management of ICANS, according to its severity grade, following Yakoub-Agha et al.[12].
Patient care pathway from screening to long-term follow-up and kinetics of complications.