Epileptic Disorders
MENUVideo/EEG findings in a KCNQ2 epileptic encephalopathy: a case report and revision of literature data Volume 15, numéro 2, June 2013
"The episode is characterised by right eye and head deviation, associated with upper limb hypertonus. Twenty seconds later, the patient shifts head and gaze towards the left, while hypertonus is maintained. The EEG shows an initial train of fast, low-voltage activity originating from the left frontal regions which gives way to a high-voltage, spike-wave activity involving the left hemisphere. Together with persistent upper limb hypertonus, bilateral eyelid myoclonias also appear, in association with an increase in respiratory frequency which is maintained until the end of the seizure. Asynchronous, bilateral, clonic jerks of the upper limbs are also evident. At this point, the EEG is characterised by high-voltage, spike-wave complexes which diffuse from the left to the right hemisphere and then give way to a right-sided, alpha-like activity. "
> Download"The first part of the video shows an interictal, burst-suppression pattern during apparent sleep. Bursts are characterised by high-voltage, delta waves, intermingled with spikes and polyspikes, and appear fairly synchronised and long-lasting, as do the suppression periods, characterised by low-voltage activity, sometimes with recognisable theta rhythms. The seizure shown in the second part of the video, specular to the first reported episode, is characterised by an initial eye and head deviation to the left, followed 20 seconds later by deviation towards the right, associated with hypertonus of the upper limbs. Similar to what was recorded during the first episode, the EEG shows an initial train of fast, low-voltage activity, originating from the right frontal regions which gives way to a high-voltage, spike-wave activity involving the left hemisphere. "