John Libbey Eurotext

Epileptic Disorders

The Educational Journal of the

The clinical pharmacology of traditional antiepileptic drugs Volume 16, numéro 4, December 2014


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1 Department of Medicine, Neurology, University of Melbourne, Melbourne
  • Mots-clés : benzodiazepines, carbamazepine, ethosuximide, mechanism of action, pharmacokinetics, phenobarbitone, phenytoin, valproate
  • DOI : 10.1684/epd.2014.0704
  • Page(s) : 395-408
  • Année de parution : 2014

Despite the availability of newer agents, a number of antiepileptic drugs have continued to be employed reasonably widely, many years after their introduction to human therapeutics. These drugs comprise phenobarbitone and some of its congeners, phenytoin, ethosuximide, carbamazepine, valproate, and certain benzodiazepines. Details of their pharmacological profiles are outlined in the following account.