Epileptic Disorders
MENUQuinidine therapy and therapeutic drug monitoring in four patients with KCNT1 mutations Volume 21, numéro 1, February 2019
TEST YOURSELF
(1) Which epilepsy syndromes are believed to show a response to quinidine therapy?
(2) Which antiepileptic drugs suppress serum quinidine concentration?
Answers
(1) Epilepsy of infancy with migrating focal seizures (EIMFS) and West syndrome.
(2) Cytochrome P450 3A4-inducing drugs, such as phenobarbital, carbamazepine, and oxcarbazepine.