John Libbey Eurotext

Medication-resistant acute focal motor seizures in a child with COVID-19 affecting the CNS Article à paraître

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Auteurs
Department of Pediatric Neurology, Golestan Medical, Educational, and Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
* Correspondance: Department of Pediatric Neurology, Golestan Medical, Educational and Research Centre, Ahvaz Jundishapur University of Medical Sciences, #90, Golestan Blvd., Ahvaz, Iran

A perfectly healthy preschool girl presented with acute repetitive focal aware motor seizures, while her brain MRI showed a lesion in the left posterior cortex. After a number of investigations, her cerebrospinal fluid PCR was positive for SARS-CoV-2. Despite receiving at least four anti-seizure medications at appropriate dosages, the seizures continued, and just after administering intravenous immunoglobulin, her seizures stopped. This dramatic response to intravenous immunoglobulin may indicate a hypothetical inflammatory process in the patient’s cortex caused by COVID-19.