John Libbey Eurotext

GAT-1 (rs2697153) and GAT-3 (rs2272400) polymorphisms are associated with febrile seizures and temporal lobe epilepsy Volume 22, numéro 2, April 2020

Auteurs
1 Department of Neurosurgery, Maastricht University Medical Center, Maastricht,
2 Academic Center for Epileptology (ACE), Maastricht University Medical Center, Maastricht,
3 School of Mental Health and Neurosciences, Maastricht University, Maastricht,
4 Department of Neurosurgery, Zuyderland Medical Center, Heerlen,
5 Department of Genetics and Cell Biology, Maastricht University, Maastricht, The Netherlands
* Correspondence: Jeroen Bisschop Department of Neurosurgery, Maastricht University Medical Center, Postbus 5800, 6202 AZ Maastricht, The Netherlands
a Authors contributed equally

Aim

The purpose of this study was to determine a possible association between two GABA transporter (GAT) single-nucleotide polymorphisms (SNPs), rs2697153 G>A in SLC6A1 (GAT-1) and rs2272400 C>T in SLC6A11 (GAT-3), and drug-resistant temporal lobe epilepsy (TLE).