John Libbey Eurotext

Functional connectivity analysis of patients with temporal lobe epilepsy displaying different ictal propagation patterns Volume 22, numéro 5, October 2020


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1 Departments of Neurology and Clinical Neurophysiology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey
2 Aziz Sancar Institute of Experimental Medicine, Department of Neuroscience, Istanbul University, Istanbul, Turkey
3 Hulusi Behçet Life Sciences Research Laboratory, Istanbul University, Istanbul, Turkey
4 Department of Physiology, Faculty of Medicine, Demiroğlu Bilim University, Istanbul, Turkey
5 Department of Physiology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey
* Correspondence: Nermin Gorkem Sirin Istanbul University Istanbul Faculty of Medicine, Department of Neurology, Capa, Fatih, Istanbul, 34390, Turkey


The pathophysiology of switch-of lateralization and bilateral temporal asynchrony, which are scalp EEG ictal propagation patterns (iPP) in temporal lobe epilepsy (TLE), is poorly understood. We aimed to analyse functional connectivity (FC) of the temporal lobe and related areas in patients with TLE with iPP (iPP-TLE) and without iPP (non-iPP TLE).