Epileptic Disorders
MENUAbsence status induced by lacosamide adjunctive therapy Volume 21, numéro 1, February 2019
TEST YOURSELF
(1) Which of the following medications can cause an aggravation of absence seizures in people with idiopathic generalized epilepsy?
A. Vigabatrin and tiagabine
B. Lacosamide
C. Carbamazepine and phenytoin
D. All of the above
(2) Lacosamide’s main mechanism of action is due to enhancement of _____ _____ of sodium channels.
A. Rapid activation
B. Slow inactivation
C. Rapid inactivation
D. Slow activation
(3) Lacosamide is a promising treatment for idiopathic generalized epilepsy, but caution is advised in patients with_____ _____ seizures.
A. Bilateral convulsive seizures
B. Myoclonic seizures
C. Absence seizures
D. All of the above
Answers
(1) D. All of the above.
(2) B. Slow inactivation.
(3) C. Absence seizures.