John Libbey Eurotext

European Journal of Dermatology


sQUIZ your knowledge: generalized hyperpigmentation and palmoplantar erythrodysesthesia Article à paraître


1 Department of Dermatology,
2 Department of Hematology,
Roskilde Hospital,
Koegevej 7-13, 4000,

A 73-year-old woman with diffuse large B-cell lymphoma, currently undergoing chemotherapy with liposomal doxorubicin, cyclophosphamide and vincristine, presented with generalized hyperpigmentation of the skin (figures 1A, B) and sharply demarcated erythema, oedema and desquamation of the palms (figure 1C) and, to a lesser degree, the soles (figure 1D). The patient complained of tightness, pain, and a burning sensation in the palms.What is your diagnosis?A short Synacthen test was normal, and a histopathological [...]